Mechanical Engineer
Senior Mechanical Engineer
Senior Mechanical Engineer / Biomedical Engineer
Resource Type: W2 OnlyPay Rate: $71/hr
Location: On-site - Santa Clara, CA
About Roche
A healthier future drives us to innovate, continuously advance science, and ensure access to healthcare for all. At Roche, we are building a world where people have more time with those they love.
We are advancing next-generation sequencing (NGS) by simplifying workflows, accelerating clinical research, and expanding access to genomic data. Our integrated solutions span from sample preparation to sequencing and bioinformatics-delivering a seamless "sample in, result out" experience.
Role Overview
The Systems Technology Group within Roche Sequencing Solutions is seeking a Senior Mechanical Engineer to design and develop advanced sequencing systems.
This is a hands-on, multidisciplinary role focused on solving complex mechanical challenges involving electro-mechanical, pneumatic, thermal, and fluidic systems.
Core Responsibilities- Design and develop mechanical sub-systems including electro-mechanical, pneumatic, fluidic, and thermal components
- Collaborate cross-functionally with electrical, materials, and consumables teams
- Develop mechanisms for automated reagent and flow cell handling
- Design and implement thermal control systems
- Lead subsystem integration, verification, and troubleshooting
- Drive design reviews and resolve technical trade-offs
- Manage timelines and technical deliverables
- Create and maintain CAD models, drawings, and specifications
- Contribute to system architecture and technical strategy
- Present technical updates and engineering decisions to stakeholders
- PhD + 1 year, OR Master's + 2 years, OR Bachelor's + 4 years of relevant experience
- Strong expertise in mechanical and electro-mechanical system design
- Experience with thermal management and precision temperature control
- Hands-on experience with fluidics systems (pumps, valves, sensors, tubing)
- Proficiency in 3D CAD tools (e.g., SolidWorks)
- Experience with manufacturing processes (machining, injection molding, 3D printing)
- Strong troubleshooting skills across hardware, software, and chemistry interfaces
- Hands-on experience with machine shop tools and prototyping technologies
- Familiarity with Python, LabVIEW, or similar tools
- Experience with simulation tools (CFD, FEA)
- Background in NGS or genomics instrumentation
- Experience in regulated product development environments
- Strong communication and interpersonal skills
- Ability to manage multiple priorities effectively
- This is a fully on-site role in Santa Clara, CA
- No relocation assistance is provided
- No requirement for fluidics/microfluidics specialization, but life sciences instrumentation experience is preferred
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