apartmentCare New EnglandplaceProvidence, 41 mi from Boston
focus include: maternal and child nutrition, lactation and milk composition, neonatal neurobehavior, follow-up and development of neonates, global health, health equity, biomarker discovery and assay development and maternal mental health. The selected...
apartmentCapital OneplaceCambridge
Senior Manager, Technical Program Management - Enterprise Data. As the Senior Manager of Technical Program Management in Capital One’s Enterprise Data and Machine Learning (EDML) division, you’ll be at the forefront of driving innovation and efficiency in our Data API ecosystem. Manager, Technical P...
business_centerHigh salary

Biomarker Study Manager, Senior Manager

apartmentBiogenplaceCambridge, 4 mi from Boston
Job Description About This Role This role is responsible for clinical study bioanalytical and biomarker operations management. The bioanalytical and biomarkers study manger is a member of the clinical study team and will contribute to study...
apartmentAbbVieplaceCambridge, 4 mi from Boston
Job Description We are seeking an experienced and highly motivated Senior Scientist I to provide scientific, operational, and logistical support for implementing biomarker strategies in multiple neurology and neuropsychiatry, psychiatry clinical...
apartmentAbbVieplaceWorcester, 41 mi from Boston
life cycle in Development: Define translational research strategy in rheumatology to support clinical success of pipeline assets, including PD/TE biomarkers, POM biomarkers, patient selection/stratification strategies, and development of novel disease...
apartmentMindlanceplaceAndover (MA), 21 mi from Boston
concentration and immunogenicity data to BioMedicine Design Project Leads and other BioTX partners. Design, develop and implement ligand-binding assays (e.g., MSD, Gyrolab, ELISA) to measure protein concentration of drug and/or biomarker and detect the presence...
apartmentPioneer Data SystemsplaceAndover (MA), 21 mi from Boston
programs. Deliver concentration and immunogenicity data to BioMedicine Design Project Leads and other BioTX partners. Design, develop and implement ligand-binding assays (e.g., MSD, Gyrolab, ELISA) to measure protein concentration of drug and/or biomarker...
apartmentMITREplaceBedford
The successful candidate for this position is a geospatial data scientist who combines a solid theoretical and technical background with the ability to formulate problems, develop and evaluate solutions, and communicate results. Apply a variety of spatial data science techniques to tackle customer c...
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Senior Principal Research Scientist, Immunology Computational Biology Fibrosis Lead

AbbVie | Cambridge | www.resume-library.com |
Job Description

The Genomics Research Center (GRC) Immunology Computational Biology group at AbbVie is seeking a highly motivated, experienced computational biology leader to play an integral role in a multi-disciplinary team focused on developing new therapies for the treatment and cure of immunological diseases.
AbbVie’s GRC is a center of excellence for bioinformatics, functional genomics, human genetics and pharmacogenomics. GRC works across all R&D including discovery and clinical development, and multiple areas such as process sciences, search and evaluation and corporate strategy.

This position will be based in Cambridge, Massachusetts. The candidate will lead a team focused on fibrotic diseases and work closely with computational biologists across the network and be embedded in research project teams in immunology discovery and precision medicine to analyze multi-omic datasets to derive insights into immunological diseases, identify novel therapeutic targets and biomarkers specific to patient cohorts and AbbVie pipeline drugs.
The successful applicant will address key project team questions related to forward and reverse translation, genomic biomarker identification and mechanistic characterization, and communicate findings to internal and external stakeholders . In addition, the candidate will contribute to presentations at scientific conferences and publications of translational findings in peer reviewed journals, new drug applications and regulatory filings.

Key Responsibilities:

 •  Partner with immunology discovery and precision medicine to perform hands on omics data analysis to address key project questions related to forward/reverse translation, genomic biomarker development and mechanistic characterization
 •  Be our fibrotic disease area representative in program teams and coordinate cross-functional projects
 •  Provide expert guidance and suggestions on experimental design and analytical insights
 •  Perform novel target identification from internal and external omics data, and advance these targets into the immunology pipeline
 •  Support target and biomarker development for enterprise-critical late-stage programs experimental medicine and clinical trials
 •  Evaluate patient stratification hypothesis for immunological diseases and integrate with clinical trial data to predict personalized treatments
 •  Develop and implement analytical approaches and best practices for novel technologies such as spatial transcriptomics, single cell sequencing and CRISPR
 •  Hire, mentor and develop scientists with high caliber and potentialSignificant Work Activities -Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)